Oral Program

Thursday, 6 July 2000
17.00-1900	Registration
Friday, 7 July 2000
08.00	Registration
INFLAMMATORY MEDIATORS
COMPLEMENT:
09.00-09.35	Classical and Alternative Pathways Neil Cooper, Scripps Research Institute, USA
	09.35-10.10 Complement Regulation Piet Eikelenboom, Free University, Amsterdam, The Netherlands
	1010-1045 The Role of Complement Anaphylatoxin C5a in Neurodegeneration: Implications in Alzheimer's Disease Giulio Maria Pasinetti, Mt. Sinai School Medicine, USA
10.45-11.05	COFFEE BREAK
ACUTE PHASE REACTANTS:
11.05-11.30	a1-ACT, a2-MAC, Serum amyloid P Ikuo Tooyama, Shiga University, Japan
FIBRINOLYSIS/COAGULATION SYSTEMS:
11.30-11.55	Fibrinolysis/coagulation Systems Haruhiko Akiyama, Tokyo Institute Psychiatry, Japan
CYCLOOXYGENASES:
11.55-12.30	COX1 and COX2 Kerry O'Banion, University of Rochester, USA
12.30 - 13.30	LUNCH BREAK
CYTOKINES:
1330-1405	IL-1/S100-b W.S.T. Griffin, University of Arkansas, USA
1405-1440	IL-6 Joachim Bauer, University of Freiburg, Germany
1440-1515	TNF-a Yong Shen, Sun Health Research Institute, USA
15.15-15.50	TGF-b Tony Wyss-Coray, University of California San Francisco, USA
15.50-16.10	COFFEE BREAK
DAY 1 ROUNDTABLE DISCUSSION/Q&A
1610-1710	Discussant Nancy Ruddle, Yale University, USA
Saturday, 8 July 2000
INFLAMMATORY CELLS
0830-0905	Microglia Mark Emmerling, Parke-Davis, USA
0905-0940	Astrocytes Robert Mrak, University of Arkansas, USA
0940-1005	Neurons Steven Barger, University of Arkansas, USA
10.05-10.25	COFFEE BREAK
OTHER MECHANISMS OF INFLAMMATORY TOXICITY
1025-1050	Ab Binding Proteins Scott Webster, University California Irvine, USA
1050-1115	Oxidative Stress Douglas Walker, Sun Health Research Institute, USA
1115-1150	RAGE and the Macrophage Scavenger Receptor David Stern, Columbia University, USA
SUMMARY-THE BASIC SCIENCE OF ALZHEIMER'S NEUROINFLAMMATION
1150-1225	Summary Patrick McGeer, University of British Columbia, Canada
12.25-13.25	LUNCH BREAK
PATHOPHYSIOLOGIC AND CLINICAL RELEVANCE
1325-1400	Transgenic and other Animal Models of Alzheimer's Neuroinflammation Sally Frautschy, University California Los Angeles, USA
1400-1435	Previous Clinical Research Harald Hampel, Ludwig-Maximillian University, Germany
FUTURE DIRECTIONS
1435-1510	Choosing the Right Drug and the Right Time for Alzheimer's Neuroinflammation Therapy John Breitner, Johns Hopkins University, USA
1510-1545	Amyloid Vaccination and its Neuroimmunologic Implications Dale Shenk, Elan Pharmaceuticals, USA
1545-1615	Neuroimmunology of Aging Caleb Finch, University of Southern California, USA
	COFFEE BREAK
DAY 2 ROUNDTABLE DISCUSSION/Q&A
1635-1730	Discussant William Hickey, Dartmouth College, USA

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